Plaque Psoriasis

Plaque Psoriasis Is an Inflammatory Skin Condition That Is Difficult to Treat Successfully1

Psoriasis, which manifests most often as plaque psoriasis, is a chronic, relapsing, autoimmune skin disorder with a genetic basis.1,2

Plaque psoriasis affects about 6.7 million adults.2

Symptoms include2:

  • Raised, discolored (red, brown,
    gray, or purple) plaques with a
    white or silvery surface
  • Cracks (fissures)
  • Bleeding
  • Itchiness
  • Irritation or pain
80-90% of people with psoriasis develop plaque psoriasis graphic

About 80% to 90%of people with psoriasis experience plaque psoriasis2

person with psoriasis graphic

Plaques most often appear on the scalp, knees, elbows,
and torso3

person with psoriasis graphic

On skin of color, plaque may appear darker, thicker and more of purple, grayish, or darker brown color3

Plaque psoriasis is rarely life-threatening, but it is often resistant to treatment.1
There are 3 general treatment modalities4:

TOPICAL AGENTS
  • Corticosteroids
  • Coal tar
  • Anthralin
  • Calcipotriene
  • Tapinarof
  • Tazarotene
  • Roflumilast topical
PHOTOTHERAPY
  • Ultraviolet B (UVB) irradiation
  • Psoralen plus ultraviolet A
    irradiation (PUVA)
SYSTEMIC AGENTS
  • Tyrosine kinase 2 inhibitors
  • Biologic therapies
    • TNF inhibitors
    • Interleukin inhibitors

 

Treatments are often used in combination.4

rotating graphic

TNFi biosimilars are now available. The FDA ensures that biosimilars and Interchangeable biosimilars are as safe and effective as their reference biologic treatments. Only Interchangeable biosimilars may be auto-substituted for the reference product by a pharmacist.5

Learn about a clinical trial of a biosimilar that demonstrated equivalence in terms of pharmacokinetics, safety, and efficacy to current treatment options